Regression of Albuminuria and Hypertension and Arrest of Severe Renal Injury by a Losartan-Hydrochlorothiazide Association in a Model of Very Advanced Nephropathy

Treatments that effectively prevent chronic kidney disease (CKD) when initiated early often yield disappointing results when started at more advanced phases. We examined the long-term evolution of renal injury in the 5/6 nephrectomy model (Nx) and the effect of an association between an AT-1 recepto...

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Detalhes bibliográficos
Main Authors: Arias, Simone Costa Alarcon, Valente, Carla Perez, Machado, Flavia Gomes, Fanelli, Camilla, Origassa, Clarice Silvia Taemi, de Brito, Thales, Camara, Niels Olsen Saraiva, Malheiros, Denise Maria Avancini Costa, Zatz, Roberto, Fujihara, Clarice Kazue
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576388/
https://ncbi.nlm.nih.gov/pubmed/23431367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056215
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