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Kinase Suppressor of Ras 1 Is Not Required for the Generation of Regulatory and Memory T Cells

The mammalian target of rapamycin (mTOR) kinase is a critical regulator of the differentiation of helper and regulatory CD4+ T cells, as well as memory CD8+ T cells. In this study, we investigated the role of the ERK signaling pathway in regulating mTOR activation in T cells. We showed that activati...

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Autori principali: Le Borgne, Marie, Filbert, Erin L., Shaw, Andrey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576348/
https://ncbi.nlm.nih.gov/pubmed/23431403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057137
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