Epigenetic inactivation of the MIR129-2 in hematological malignancies

BACKGROUND: MIR129-2 has been shown to be a tumor suppressor microRNA hypermethylated in epithelial cancers. PATIENTS AND METHODS: Epigenetic inactivation of MIR129-2 was studied by methylation-specific PCR (MSP) in 13 cell lines (eight myeloma and five lymphoma), 15 normal controls and 344 primary...

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Hlavní autoři: Wong, Kwan-Yeung, Yim, Rita Lok-Hay, Kwong, Yok-Lam, Leung, Chung-Ying, Hui, Pak-Kwan, Cheung, Florence, Liang, Raymond, Jin, Dong-Yan, Chim, Chor-Sang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576298/
https://ncbi.nlm.nih.gov/pubmed/23406679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-16
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