Incidence and patterns of ALK FISH abnormalities seen in a large unselected series of lung carcinomas

BACKGROUND: Anaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangements have been reported in 2-13% of patients with non-small cell lung cancer (NSCLC). Patients with ALK rearrangements do not respond to EGFR-specific tyrosine kinase inhibitors (TKIs); however, they do benefit from small...

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Detalles Bibliográficos
Autores principales: Dai, Zunyan, Kelly, JoAnn C, Meloni-Ehrig, Aurelia, Slovak, Marilyn L, Boles, Debra, Christacos, Nicole C, Bryke, Christine R, Schonberg, Steven A, Otani-Rosa, Jennifer, Pan, Qiulu, Ho, Albert K, Sanders, Heather R, Zhang, Zhong J, Jones, Dan, Mowrey, Philip N
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576271/
https://ncbi.nlm.nih.gov/pubmed/23198868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-5-44
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