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Incidence and patterns of ALK FISH abnormalities seen in a large unselected series of lung carcinomas
BACKGROUND: Anaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangements have been reported in 2-13% of patients with non-small cell lung cancer (NSCLC). Patients with ALK rearrangements do not respond to EGFR-specific tyrosine kinase inhibitors (TKIs); however, they do benefit from small...
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Main Authors: | , , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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BioMed Central
2012
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3576271/ https://ncbi.nlm.nih.gov/pubmed/23198868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-5-44 |
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