Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli

BACKGROUND: Wide use of ciprofloxacin and levofloxacin has often led to increased resistance. The resistance rate to these two agents varies in different clinical isolates of Enterobacteriaceae. Mutations of GyrA within the quinolone resistance-determining regions have been found to be the main mech...

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Autors principals: Fu, Yingmei, Zhang, Wenli, Wang, Hong, Zhao, Song, Chen, Yang, Meng, Fanfei, Zhang, Ying, Xu, Hui, Chen, Xiaobei, Zhang, Fengmin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576228/
https://ncbi.nlm.nih.gov/pubmed/23295059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-13-8
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