Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli

BACKGROUND: Wide use of ciprofloxacin and levofloxacin has often led to increased resistance. The resistance rate to these two agents varies in different clinical isolates of Enterobacteriaceae. Mutations of GyrA within the quinolone resistance-determining regions have been found to be the main mech...

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Main Authors: Fu, Yingmei, Zhang, Wenli, Wang, Hong, Zhao, Song, Chen, Yang, Meng, Fanfei, Zhang, Ying, Xu, Hui, Chen, Xiaobei, Zhang, Fengmin
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576228/
https://ncbi.nlm.nih.gov/pubmed/23295059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-13-8
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