Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli

BACKGROUND: Wide use of ciprofloxacin and levofloxacin has often led to increased resistance. The resistance rate to these two agents varies in different clinical isolates of Enterobacteriaceae. Mutations of GyrA within the quinolone resistance-determining regions have been found to be the main mech...

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Detalhes bibliográficos
Main Authors: Fu, Yingmei, Zhang, Wenli, Wang, Hong, Zhao, Song, Chen, Yang, Meng, Fanfei, Zhang, Ying, Xu, Hui, Chen, Xiaobei, Zhang, Fengmin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576228/
https://ncbi.nlm.nih.gov/pubmed/23295059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-13-8
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