Genetic Variation Throughout the Folate Metabolic Pathway Influences Negative Symptom Severity in Schizophrenia

Low serum folate levels previously have been associated with negative symptom risk in schizophrenia, as has the hypofunctional 677C>T variant of the MTHFR gene. This study examined whether other missense polymorphisms in folate-regulating enzymes, in concert with MTHFR, influence negative symptom...

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Main Authors: Roffman, Joshua L., Brohawn, David G., Nitenson, Adam Z., Macklin, Eric A., Smoller, Jordan W., Goff, Donald C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576161/
https://ncbi.nlm.nih.gov/pubmed/22021659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbr150
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