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Genetic Variation Throughout the Folate Metabolic Pathway Influences Negative Symptom Severity in Schizophrenia

Low serum folate levels previously have been associated with negative symptom risk in schizophrenia, as has the hypofunctional 677C>T variant of the MTHFR gene. This study examined whether other missense polymorphisms in folate-regulating enzymes, in concert with MTHFR, influence negative symptom...

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Detalhes bibliográficos
Main Authors: Roffman, Joshua L., Brohawn, David G., Nitenson, Adam Z., Macklin, Eric A., Smoller, Jordan W., Goff, Donald C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576161/
https://ncbi.nlm.nih.gov/pubmed/22021659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbr150
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