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Translocation and Stability of Replicative DNA Helicases upon Encountering DNA-Protein Cross-links

DNA-protein cross-links (DPCs) are formed when cells are exposed to various DNA-damaging agents. Because DPCs are extremely large, steric hindrance conferred by DPCs is likely to affect many aspects of DNA transactions. In DNA replication, DPCs are first encountered by the replicative helicase that...

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Detalhes bibliográficos
Main Authors: Nakano, Toshiaki, Miyamoto-Matsubara, Mayumi, Shoulkamy, Mahmoud I., Salem, Amir M. H., Pack, Seung Pil, Ishimi, Yukio, Ide, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576070/
https://ncbi.nlm.nih.gov/pubmed/23283980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419358
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