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Translocation and Stability of Replicative DNA Helicases upon Encountering DNA-Protein Cross-links

DNA-protein cross-links (DPCs) are formed when cells are exposed to various DNA-damaging agents. Because DPCs are extremely large, steric hindrance conferred by DPCs is likely to affect many aspects of DNA transactions. In DNA replication, DPCs are first encountered by the replicative helicase that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nakano, Toshiaki, Miyamoto-Matsubara, Mayumi, Shoulkamy, Mahmoud I., Salem, Amir M. H., Pack, Seung Pil, Ishimi, Yukio, Ide, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576070/
https://ncbi.nlm.nih.gov/pubmed/23283980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.419358
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