Identification of the Low Density Lipoprotein (LDL) Receptor-related Protein-1 Interactome in Central Nervous System Myelin Suggests a Role in the Clearance of Necrotic Cell Debris

In the central nervous system (CNS), fast neuronal signals are facilitated by the oligodendrocyte-produced myelin sheath. Oligodendrocyte turnover or injury generates myelin debris that is usually promptly cleared by phagocytic cells. Failure to remove dying oligodendrocytes leads to accumulation of...

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Main Authors: Fernandez-Castaneda, Anthony, Arandjelovic, Sanja, Stiles, Travis L., Schlobach, Ryan K., Mowen, Kerri A., Gonias, Steven L., Gaultier, Alban
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Neurobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576060/
https://ncbi.nlm.nih.gov/pubmed/23264627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.384693
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