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Characterizing antiprion compounds based on their binding properties to prion proteins: Implications as medical chaperones
A variety of antiprion compounds have been reported that are effective in ex vivo and in vivo treatment experiments. However, the molecular mechanisms for most of these compounds remain unknown. Here we classified antiprion mechanisms into four categories: I, specific conformational stabilization; I...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575857/ https://ncbi.nlm.nih.gov/pubmed/23081827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2180 |
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