Discovery of a multipotent chaperone, 1-(2,6-Difluorobenzylamino)-3-(1,2,3,4-tetrahydrocarbazol-9-yl)-propan-2-ol with the inhibitory effects on the proliferation of prion, cancer as well as influenza virus

We previously discovered three carbazole derivatives, GJP14 (1-piperidinylmethyl-2-(1-oxo-6-methyl-1,2,3,4-tetrahydrocarbazol-9-yl)-ethan-1-ol) with anti-prion activity, GJC29 (benzylamino-3-(1,2,3,4-tetrahydrocarbazol-9-yl)-propan-2-ol) with anti-cancer activity, and THC19 (1-piperidinylmethyl-2-(1...

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Bibliographic Details
Published in:Prion
Main Authors: Yamashita, Satoshi, Honda, Ryo, Fukuoka, Mayuko, Kimura, Tsutomu, Hosokawa-Muto, Junji, Kuwata, Kazuo
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
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Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984644/
https://ncbi.nlm.nih.gov/pubmed/31971853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2020.1714372
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