Clostridium difficile TcdC protein binds four-stranded G-quadruplex structures

Clostridium difficile infections are increasing worldwide due to emergence of virulent strains. Infections can result in diarrhea and potentially fatal pseudomembranous colitis. The main virulence factors of C. difficile are clostridial toxins TcdA and TcdB. Transcription of the toxins is positively...

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Détails bibliographiques
Auteurs principaux: van Leeuwen, Hans C., Bakker, Dennis, Steindel, Philip, Kuijper, Ed J., Corver, Jeroen
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
Molecular Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575817/
https://ncbi.nlm.nih.gov/pubmed/23303781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1448
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