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tcdC Genotypes Associated with Severe TcdC Truncation in an Epidemic Clone and Other Strains of Clostridium difficile

Severe Clostridium difficile associated disease is associated with outbreaks of the recently described BI/NAP1 epidemic clone. This clone is characterized by an 18-bp deletion in the tcdC gene and increased production of toxins A and B in vitro. TcdC is a putative negative regulator of toxin A&B...

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Detalhes bibliográficos
Main Authors: Curry, Scott R., Marsh, Jane W., Muto, Carlene A., O'Leary, Mary M., Pasculle, A. William, Harrison, Lee H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828959/
https://ncbi.nlm.nih.gov/pubmed/17035492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01599-06
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