tcdC Genotypes Associated with Severe TcdC Truncation in an Epidemic Clone and Other Strains of Clostridium difficile

Severe Clostridium difficile associated disease is associated with outbreaks of the recently described BI/NAP1 epidemic clone. This clone is characterized by an 18-bp deletion in the tcdC gene and increased production of toxins A and B in vitro. TcdC is a putative negative regulator of toxin A&B...

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Bibliographic Details
Main Authors: Curry, Scott R., Marsh, Jane W., Muto, Carlene A., O'Leary, Mary M., Pasculle, A. William, Harrison, Lee H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Bacteriology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828959/
https://ncbi.nlm.nih.gov/pubmed/17035492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01599-06
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