Clostridium difficile TcdC protein binds four-stranded G-quadruplex structures

Clostridium difficile infections are increasing worldwide due to emergence of virulent strains. Infections can result in diarrhea and potentially fatal pseudomembranous colitis. The main virulence factors of C. difficile are clostridial toxins TcdA and TcdB. Transcription of the toxins is positively...

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Bibliografski detalji
Glavni autori: van Leeuwen, Hans C., Bakker, Dennis, Steindel, Philip, Kuijper, Ed J., Corver, Jeroen
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Molecular Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575817/
https://ncbi.nlm.nih.gov/pubmed/23303781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1448
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