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Clostridium difficile TcdC protein binds four-stranded G-quadruplex structures

Clostridium difficile infections are increasing worldwide due to emergence of virulent strains. Infections can result in diarrhea and potentially fatal pseudomembranous colitis. The main virulence factors of C. difficile are clostridial toxins TcdA and TcdB. Transcription of the toxins is positively...

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Bibliografische gegevens
Hoofdauteurs: van Leeuwen, Hans C., Bakker, Dennis, Steindel, Philip, Kuijper, Ed J., Corver, Jeroen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575817/
https://ncbi.nlm.nih.gov/pubmed/23303781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1448
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