Two-dimensional intact mitochondrial DNA agarose electrophoresis reveals the structural complexity of the mammalian mitochondrial genome

The mitochondrial genome exists in numerous structural conformations, complicating the study of mitochondrial DNA (mtDNA) metabolism. Here, we describe the development of 2D intact mtDNA agarose gel electrophoresis (2D-IMAGE) for the separation and detection of approximately two-dozen distinct topoi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kolesar, Jill E., Wang, Catherine Y., Taguchi, Yumiko V., Chou, Shih-Hsuan, Kaufman, Brett A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2013
Gaiak:
Methods Online
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575812/
https://ncbi.nlm.nih.gov/pubmed/23275548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1324
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