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Two-dimensional intact mitochondrial DNA agarose electrophoresis reveals the structural complexity of the mammalian mitochondrial genome

The mitochondrial genome exists in numerous structural conformations, complicating the study of mitochondrial DNA (mtDNA) metabolism. Here, we describe the development of 2D intact mtDNA agarose gel electrophoresis (2D-IMAGE) for the separation and detection of approximately two-dozen distinct topoi...

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Sonraí Bibleagrafaíochta
Main Authors: Kolesar, Jill E., Wang, Catherine Y., Taguchi, Yumiko V., Chou, Shih-Hsuan, Kaufman, Brett A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575812/
https://ncbi.nlm.nih.gov/pubmed/23275548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1324
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