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Rev3, the catalytic subunit of Polζ, is required for maintaining fragile site stability in human cells

It has been long speculated that mammalian Rev3 plays an important, yet unknown role(s) during mammalian development, as deletion of Rev3 causes embryonic lethality in mice, whereas no other translesion DNA synthesis polymerases studied to date are required for mouse embryo development. Here, we rep...

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Autori principali: Bhat, Audesh, Andersen, Parker L., Qin, Zhoushuai, Xiao, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575803/
https://ncbi.nlm.nih.gov/pubmed/23303771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1442
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