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Rev3, the catalytic subunit of Polζ, is required for maintaining fragile site stability in human cells

It has been long speculated that mammalian Rev3 plays an important, yet unknown role(s) during mammalian development, as deletion of Rev3 causes embryonic lethality in mice, whereas no other translesion DNA synthesis polymerases studied to date are required for mouse embryo development. Here, we rep...

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Detalhes bibliográficos
Main Authors: Bhat, Audesh, Andersen, Parker L., Qin, Zhoushuai, Xiao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575803/
https://ncbi.nlm.nih.gov/pubmed/23303771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1442
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