Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs

The thymine analog 5-chlorouridine, first reported in the 1950s as anti-tumor agent, is known as an effective mutagen, clastogen and toxicant as well as an effective inducer of sister-chromatid exchange. Recently, the first microorganism with a chemically different genome was reported; the selected...

Full description

Saved in:
Bibliographic Details
Main Authors: Patra, Amritraj, Harp, Joel, Pallan, Pradeep S., Zhao, Linlin, Abramov, Mikhail, Herdewijn, Piet, Egli, Martin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575798/
https://ncbi.nlm.nih.gov/pubmed/23275540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1316
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items