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Binding characteristics of [(3)H]-JSM10292: a new cell membrane-permeant non-peptide bradykinin B(2) receptor antagonist
BACKGROUND AND PURPOSE: A (3)H-labelled derivative of the novel small-molecule bradykinin (BK) B(2) receptor antagonist JSM10292 was used to directly study its binding properties to human and animal B(2) receptors in intact cells and to closely define its binding site. EXPERIMENTAL APPROACH: Equilib...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Publishing Ltd
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575783/ https://ncbi.nlm.nih.gov/pubmed/22646218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02054.x |
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