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Binding characteristics of [(3)H]-JSM10292: a new cell membrane-permeant non-peptide bradykinin B(2) receptor antagonist

BACKGROUND AND PURPOSE: A (3)H-labelled derivative of the novel small-molecule bradykinin (BK) B(2) receptor antagonist JSM10292 was used to directly study its binding properties to human and animal B(2) receptors in intact cells and to closely define its binding site. EXPERIMENTAL APPROACH: Equilib...

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Bibliografski detalji
Glavni autori: Faussner, A, Schüssler, S, Feierler, J, Bermudez, M, Pfeifer, J, Schnatbaum, K, Tradler, T, Jochum, M, Wolber, G, Gibson, C
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575783/
https://ncbi.nlm.nih.gov/pubmed/22646218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02054.x
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