Binding characteristics of [(3)H]-JSM10292: a new cell membrane-permeant non-peptide bradykinin B(2) receptor antagonist

BACKGROUND AND PURPOSE: A (3)H-labelled derivative of the novel small-molecule bradykinin (BK) B(2) receptor antagonist JSM10292 was used to directly study its binding properties to human and animal B(2) receptors in intact cells and to closely define its binding site. EXPERIMENTAL APPROACH: Equilib...

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Detalhes bibliográficos
Main Authors: Faussner, A, Schüssler, S, Feierler, J, Bermudez, M, Pfeifer, J, Schnatbaum, K, Tradler, T, Jochum, M, Wolber, G, Gibson, C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575783/
https://ncbi.nlm.nih.gov/pubmed/22646218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02054.x
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