The oligopeptide DT-2 is a specific PKG I inhibitor only in vitro, not in living cells

BACKGROUND AND PURPOSE: cGMP is involved in the regulation of many cellular processes including cardiac and smooth muscle contractility, aldosterone synthesis and inhibition of platelet activation. Intracellular effects cGMP are mediated by cGMP-dependent PKs, cGMP-regulated PDEs and cGMP-gated ion...

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Detalhes bibliográficos
Main Authors: Gambaryan, Stepan, Butt, Elke, Kobsar, Anna, Geiger, Joerg, Rukoyatkina, Natalia, Parnova, Rimma, Nikolaev, Viacheslav O, Walter, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575782/
https://ncbi.nlm.nih.gov/pubmed/22612416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02044.x
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