Corticosteroid insensitivity is reversed by formoterol via phosphoinositide-3-kinase inhibition

BACKGROUND AND PURPOSE: Patients with chronic obstructive pulmonary disease (COPD) show a poor response to corticosteroids, which has been linked to oxidative stress. Here we show that the long-acting β(2)-agonist formoterol (FM) reversed corticosteroid insensitivity under oxidative stress via inhib...

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Main Authors: Rossios, C, To, Y, Osoata, G, Ito, M, Barnes, PJ, Ito, K
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2012
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575778/
https://ncbi.nlm.nih.gov/pubmed/22251095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01864.x
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