Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia

Immune targeting of B-cell malignancies using chimeric antigen receptors (CARs) is a promising new approach, but critical factors impacting CAR efficacy remain unclear. To test the suitability of targeting CD22 on precursor B-cell acute lymphoblastic leukemia (BCP-ALL), lymphoblasts from 111 patient...

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Autores principales: Haso, Waleed, Lee, Daniel W., Shah, Nirali N., Stetler-Stevenson, Maryalice, Yuan, Constance M., Pastan, Ira H., Dimitrov, Dimiter S., Morgan, Richard A., FitzGerald, David J., Barrett, David M., Wayne, Alan S., Mackall, Crystal L., Orentas, Rimas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2013
Materias:
Lymphoid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575759/
https://ncbi.nlm.nih.gov/pubmed/23243285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-438002
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