Chd5 Requires PHD-mediated Histone 3 Binding for Tumor Suppression

ChromodomainHelicase DNA-binding protein 5 (CHD5) is a tumor suppressor mapping to 1p36—a genomic region frequently deleted in human cancer. Although CHD5 belongs to the CHD family of chromatin remodeling proteins, whether its tumor suppressive role involves an interaction with chromatin is unknown....

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Bibliografiske detaljer
Main Authors: Paul, Shilpi, Kuo, Alex, Schalch, Thomas, Vogel, Hannes, Joshua-Tor, Leemor, McCombie, W. Richard, Gozani, Or, Hammell, Molly, Mills, Alea A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575599/
https://ncbi.nlm.nih.gov/pubmed/23318260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.12.009
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