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The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming

One undisputed milestone of traditional oncology is neoplastic progression, which consists of a progressive selection of dedifferentiated cells driven by a chance sequence of genetic mutations. Recently it has been demonstrated that the overexpression of well-defined transcription factors reprograms...

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Détails bibliographiques
Auteurs principaux: Marzi, Ilaria, Cipolleschi, Maria Grazia, D'Amico, Massimo, Stivarou, Theodora, Rovida, Elisabetta, Vinci, Maria Cristina, Pandolfi, Silvia, Dello Sbarba, Persio, Stecca, Barbara, Olivotto, Massimo
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575464/
https://ncbi.nlm.nih.gov/pubmed/23287475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23200
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