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Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9

The p53 gene has been implicated in many cancers due to its frequent mutations as well as mutations in other genes whose proteins directly affect p53’s functions. In addition, high expression of p53 [wild-type (WT) or mutant] has been found in the cytoplasm of many tumor cells, and studies have asso...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chee, Jacqueline L.Y., Saidin, Suzan, Lane, David P., Leong, Sai Mun, Noll, Jacqueline E., Neilsen, Paul M., Phua, Yi Ting, Gabra, Hani, Lim, Tit Meng
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Landes Bioscience 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575457/
https://ncbi.nlm.nih.gov/pubmed/23255126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23054
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