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Wild-type and mutant p53 proteins interact with mitochondrial caspase-3

Caspases play a key role in the apoptotic pathway by virtue of their ability to cleave key protein substrates within the dying cell. Caspases are produced as inactive zymogens, and need to become proteolytically processed in order to become active. A key executioner caspase, caspase-3, has previousl...

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Detalles Bibliográficos
Main Authors: Frank, Amanda K, Pietsch, E Christine, Dumont, Patrick, Tao, Joy, Murphy, Maureen E
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100564/
https://ncbi.nlm.nih.gov/pubmed/21307660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.8.14906
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