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Wild-type and mutant p53 proteins interact with mitochondrial caspase-3
Caspases play a key role in the apoptotic pathway by virtue of their ability to cleave key protein substrates within the dying cell. Caspases are produced as inactive zymogens, and need to become proteolytically processed in order to become active. A key executioner caspase, caspase-3, has previousl...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100564/ https://ncbi.nlm.nih.gov/pubmed/21307660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.8.14906 |
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