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Preparation and in vitro and in vivo characterization of cyclosporin A-loaded, PEGylated chitosan-modified, lipid-based nanoparticles

BACKGROUND AND METHODS: A new cyclosporin A-loaded, PEGylated chitosan-modified lipid-based nanoparticle was developed to improve upon the formulation of cyclosporin A. PEGylated chitosan, synthesized in three steps using mild reaction conditions, was used to modify the nanoparticles. Cyclosporin A-...

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Detalhes bibliográficos
Main Authors: Zhang, Ling, Zhao, Zhi-Liang, Wei, Xiao-Hong, Liu, Jin-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575177/
https://ncbi.nlm.nih.gov/pubmed/23429854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S39685
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