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Serratiopeptidase Loaded Chitosan Nanoparticles by Polyelectrolyte Complexation: In Vitro and In Vivo Evaluation

The aim of the present study was to formulate serratiopeptidase (SER)-loaded chitosan (CS) nanoparticles for oral delivery. SER is a proteolytic enzyme which is very sensitive to change in temperature and pH. SER-loaded CS nanoparticles were fabricated by ionic gelation method using tripolyphosphate...

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Библиографические подробности
Опубликовано в: :AAPS PharmSciTech
Главные авторы: Mali, Nitin, Wavikar, Preeti, Vavia, Pradeep
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309803/
https://ncbi.nlm.nih.gov/pubmed/25171974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0201-0
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