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Optimized Chitosan/Anion Polyelectrolyte Complex Based Inserts for Vaginal Delivery of Fluconazole: In Vitro/In Vivo Evaluation

(1) Background: Fluconazole, used orally for vaginal candidiasis, has reported gastrointestinal side effects. Therefore, researchers directed towards the drug vaginal delivery. However, vaginal delivery is limited by poor retention and leakage. Thus, this work aimed at exploring chitosan/anion polye...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Darwesh, Bayan, Aldawsari, Hibah M., Badr-Eldin, Shaimaa M.
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321472/
https://ncbi.nlm.nih.gov/pubmed/30424501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040227
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