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Optimized Chitosan/Anion Polyelectrolyte Complex Based Inserts for Vaginal Delivery of Fluconazole: In Vitro/In Vivo Evaluation

(1) Background: Fluconazole, used orally for vaginal candidiasis, has reported gastrointestinal side effects. Therefore, researchers directed towards the drug vaginal delivery. However, vaginal delivery is limited by poor retention and leakage. Thus, this work aimed at exploring chitosan/anion polye...

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Vydáno v:Pharmaceutics
Hlavní autoři: Darwesh, Bayan, Aldawsari, Hibah M., Badr-Eldin, Shaimaa M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321472/
https://ncbi.nlm.nih.gov/pubmed/30424501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10040227
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