Impaired discrimination learning in mice lacking the NMDA receptor NR2A subunit

N-Methyl-D-aspartate receptors (NMDARs) mediate certain forms of synaptic plasticity and learning. We used a touchscreen system to assess NR2A subunit knockout mice (KO) for (1) pairwise visual discrimination and reversal learning and (2) acquisition and extinction of an instrumental response requir...

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Bibliografiske detaljer
Main Authors: Brigman, Jonathan L., Feyder, Michael, Saksida, Lisa M., Bussey, Timothy J., Mishina, Masayoshi, Holmes, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575092/
https://ncbi.nlm.nih.gov/pubmed/18230672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.777308
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