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Enhanced nociception by exogenous and endogenous substance P given into the spinal cord in mice lacking NR(2)A/ε(1), an NMDA receptor subunit

In capsaicin-pretreated mice, the nociceptive responses induced by intrathecally (i.t.) administered substance P (SP) were enhanced by N-methyl-D-aspartate (NMDA)-type receptor antagonists, dizocilpine (MK801) and D-2-amino-5-phosphonopentanoate (D-AP5) in a dose-dependent manner. Similar enhancemen...

詳細記述

保存先:
書誌詳細
主要な著者: Inoue, Makoto, Mishina, Masayoshi, Ueda, Hiroshi
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571840/
https://ncbi.nlm.nih.gov/pubmed/10694228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703056
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