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Back to the Future: Mechanism-Based, Mutation-Specific Combination Chemoprevention with a Synthetic Lethality Approach

There is an increasing recognition that the mutations accompanying carcinogenesis may provide a window of therapeutic advantage designated synthetic lethality, an example of which is reported in this issue of the journal by Huang and colleagues (beginning on page 666). First discovered and studied i...

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Autors principals: Meyskens, Frank L., Gerner, Eugene W.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574813/
https://ncbi.nlm.nih.gov/pubmed/21543341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0162
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