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Approaches to Identifying Synthetic Lethal Interactions in Cancer
Targeting synthetic lethal interactions is a promising new therapeutic approach to exploit specific changes that occur within cancer cells. Multiple approaches to investigate these interactions have been developed and successfully implemented, including chemical, siRNA, shRNA, and CRISPR library scr...
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| Udgivet i: | Yale J Biol Med |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
YJBM
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4445436/ https://ncbi.nlm.nih.gov/pubmed/26029013 |
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