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Approaches to Identifying Synthetic Lethal Interactions in Cancer

Targeting synthetic lethal interactions is a promising new therapeutic approach to exploit specific changes that occur within cancer cells. Multiple approaches to investigate these interactions have been developed and successfully implemented, including chemical, siRNA, shRNA, and CRISPR library scr...

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Detalhes bibliográficos
Publicado no:Yale J Biol Med
Main Authors: Thompson, Jordan M., Nguyen, Quy H., Singh, Manpreet, Razorenova, Olga V.
Formato: Artigo
Idioma:Inglês
Publicado em: YJBM 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445436/
https://ncbi.nlm.nih.gov/pubmed/26029013
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