Approaches to Identifying Synthetic Lethal Interactions in Cancer

Targeting synthetic lethal interactions is a promising new therapeutic approach to exploit specific changes that occur within cancer cells. Multiple approaches to investigate these interactions have been developed and successfully implemented, including chemical, siRNA, shRNA, and CRISPR library scr...

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Bibliografski detalji
Izdano u:Yale J Biol Med
Glavni autori: Thompson, Jordan M., Nguyen, Quy H., Singh, Manpreet, Razorenova, Olga V.
Format: Artigo
Jezik:Inglês
Izdano: YJBM 2015
Teme:
Review
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445436/
https://ncbi.nlm.nih.gov/pubmed/26029013
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