INCREASE IN ACTIVATED PROTEIN C MEDIATES ACUTE TRAUMATIC COAGULOPATHY IN MICE

In severely injured and hypoperfused trauma patients, endogenous acute coagulopathy (EAC) is associated with an increased morbidity and mortality. Recent human data correlate this coagulopathy with activation of the protein C pathway. To examine the mechanistic role of protein C in the development o...

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Hlavní autoři: Chesebro, Brian B., Rahn, Pamela, Carles, Michel, Esmon, Charles T., Xu, Jun, Brohi, Karim, Frith, Daniel, Pittet, Jean-François, Cohen, Mitchell J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574570/
https://ncbi.nlm.nih.gov/pubmed/19333141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181a5a632
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