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Critical Role of Activated Protein C in Early Coagulopathy and Later Organ Failure, Infection and Death in Trauma Patients

BACKGROUND: Recent studies have identified an acute traumatic coagulopathy that is present on admission to the hospital and is independent of iatrogenic causes. We have previously reported that this coagulopathy is due to the association of severe injury and shock and is characterized by a decrease...

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Detalhes bibliográficos
Main Authors: Cohen, Mitchell Jay, Call, Mariah, Nelson, Mary, Calfee, Carolyn S., Esmon, Charles T, Brohi, Karim, Pittet, Jean Francois
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549308/
https://ncbi.nlm.nih.gov/pubmed/22133894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0b013e318235d9e6
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