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Critical Role of Activated Protein C in Early Coagulopathy and Later Organ Failure, Infection and Death in Trauma Patients

BACKGROUND: Recent studies have identified an acute traumatic coagulopathy that is present on admission to the hospital and is independent of iatrogenic causes. We have previously reported that this coagulopathy is due to the association of severe injury and shock and is characterized by a decrease...

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Autori principali: Cohen, Mitchell Jay, Call, Mariah, Nelson, Mary, Calfee, Carolyn S., Esmon, Charles T, Brohi, Karim, Pittet, Jean Francois
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549308/
https://ncbi.nlm.nih.gov/pubmed/22133894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0b013e318235d9e6
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