Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway

Neutrophil apoptosis and subsequent nonphlogistic clearance by surrounding phagocytes are key to the successful resolution of neutrophilic inflammation, with dysregulated apoptosis reported in multiple human inflammatory diseases. Enhancing neutrophil apoptosis has proresolution and anti-inflammator...

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Bibliografische gegevens
Hoofdauteurs: Lucas, Christopher D., Allen, Keith C., Dorward, David A., Hoodless, Laura J., Melrose, Lauren A., Marwick, John A., Tucker, Carl S., Haslett, Christopher, Duffin, Rodger, Rossi, Adriano G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Federation of American Societies for Experimental Biology 2013
Onderwerpen:
Research Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574292/
https://ncbi.nlm.nih.gov/pubmed/23195034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-218990
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