Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network

Sphingosine-1-phosphate (S1P), a ligand for 5 specific receptors, is a potent lipid mediator that plays important roles in lymphocyte trafficking and immune responses. S1P is produced inside cells and therefore must be secreted to exert its effects through these receptors. Spinster 2 (Spns2) is one...

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Detalhes bibliográficos
Main Authors: Nagahashi, Masayuki, Kim, Eugene Y., Yamada, Akimitsu, Ramachandran, Subramaniam, Allegood, Jeremy C., Hait, Nitai C., Maceyka, Michael, Milstien, Sheldon, Takabe, Kazuaki, Spiegel, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574288/
https://ncbi.nlm.nih.gov/pubmed/23180825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-219618
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