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Emetine optimally facilitates nascent chain puromycylation and potentiates the RiboPuromycylation Method (RPM) applied to inert cells

We previously described the RiboPuromyclation method (RPM) to visualize and quantitate translating ribosomes in fixed and permeabilized cells by standard immunofluorescence. RPM is based on puromycylation of nascent chains bound to translating ribosomes followed by detection of puromycylated nascent...

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Bibliografske podrobnosti
Main Authors: David, Alexandre, Bennink, Jack R., Yewdell, Jonathan W.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574230/
https://ncbi.nlm.nih.gov/pubmed/23229864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-012-1063-8
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