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Glutamate biosensor imaging reveals dysregulation of glutamatergic pathways in a model of developmental cortical malformation

Cortical malformations can cause intractable epilepsy, but the underlying epileptogenic mechanisms are poorly understood. We used high-speed glutamate biosensor imaging to ask how glutamatergic signaling is altered in cortical malformations induced by neonatal freeze-lesions (FL). In non-lesion neoc...

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Detalhes bibliográficos
Main Authors: Dulla, CG, Tani, H, Brill, J, Reimer, RJ, Huguenard, JR
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574209/
https://ncbi.nlm.nih.gov/pubmed/22982711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.09.001
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