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Gabapentin attenuates hyperexcitability in the freeze-lesion model of developmental cortical malformation

Developmental cortical malformations are associated with a high incidence of drug-resistant epilepsy. The underlying epileptogenic mechanisms, however, are poorly understood. In rodents, cortical malformations can be modeled using neonatal freeze-lesion (FL), which has been shown to cause in vitro c...

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Bibliografiske detaljer
Main Authors: Andresen, Lauren, Hampton, David, Taylor, Amaro, Morel, Lydie, Yang, Yongjie, Maguire, Jamie, Dulla, Chris G.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179994/
https://ncbi.nlm.nih.gov/pubmed/25158291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.08.022
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