Cyclopropyl- and Methyl-Containing Inhibitors of Neuronal Nitric Oxide Synthase

Inhibitors of neuronal nitric oxide synthase have been proposed as therapeutics for the treatment of different types of neurological disorders. On the basis of a cis-3,4-pyrrolidine scaffold, a series of trans-cyclopropyl- and methyl-containing nNOS inhibitors have been synthesized. The insertion of...

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Detalhes bibliográficos
Main Authors: Li, Huiying, Xue, Fengtian, Kraus, James M., Ji, Haitao, Labby, Kristin Jansen, Mataka, Jan, Delker, Silvia L., Martásek, Pavel, Roman, Linda J., Poulos, Thomas L., Silverman, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574199/
https://ncbi.nlm.nih.gov/pubmed/23352768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.12.019
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