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Selective Inhibition of Extracellular Thioredoxin by Asymmetric Disulfides

Whereas the role of mammalian thioredoxin (Trx) as an intracellular protein cofactor is widely appreciated, its function in the extracellular environment is not well understood. Only few extracellular targets of Trx-mediated thiol-disulfide exchange are known. For example, Trx activates extracellula...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DiRaimondo, Thomas R., Plugis, Nicholas M., Jin, Xi, Khosla, Chaitan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574193/
https://ncbi.nlm.nih.gov/pubmed/23327656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301775s
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