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Selective Inhibition of Extracellular Thioredoxin by Asymmetric Disulfides

Whereas the role of mammalian thioredoxin (Trx) as an intracellular protein cofactor is widely appreciated, its function in the extracellular environment is not well understood. Only few extracellular targets of Trx-mediated thiol-disulfide exchange are known. For example, Trx activates extracellula...

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Bibliografiske detaljer
Main Authors: DiRaimondo, Thomas R., Plugis, Nicholas M., Jin, Xi, Khosla, Chaitan
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574193/
https://ncbi.nlm.nih.gov/pubmed/23327656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301775s
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