The Anti-Migratory Effects of FKBPL and Its Peptide Derivative, AD-01: Regulation of CD44 and the Cytoskeletal Pathway

FK506 binding protein-like (FKBPL) and its peptide derivatives exert potent anti-angiogenic activity in vitro and in vivo and control tumour growth in xenograft models, when administered exogenously. However, the role of endogenous FKBPL in angiogenesis is not well characterised. Here we investigate...

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Main Authors: Yakkundi, Anita, McCallum, Lynn, O’Kane, Anthony, Dyer, Hayder, Worthington, Jenny, McKeen, Hayley D., McClements, Lana, Elliott, Christopher, McCarthy, Helen O., Hirst, David G., Robson, Tracy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574160/
https://ncbi.nlm.nih.gov/pubmed/23457460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055075
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